The number of students at college has fallen by around 120,000 since the SNP came to power in 2007, according to statistics.
A total of 257,913 full and part-time students were at college in 2011-12, down 121,320 from 2007-08, figures from the Scottish Funding Council show.
Over the five-year period, the number of people studying full-time at college rose by 19%, to stand at 81,373 last year.
The Scottish Government highlighted the record number of 16 to 24-year-olds on a full-time, funded college course in 2011-12, at 61,304. But opposition politicians blasted the SNP administration for the overall fall in student numbers.
The Scottish Government is "trying to hide the shameful reality of 121,000 fewer students in our colleges compared to when the SNP came to power", said Labour education spokesman Hugh Henry.
There have been "massive cuts in the numbers of part-time students which is hitting hardest in our poorest communities", he said.
He added: "The SNP are no friends of our colleges. Scotland's colleges remain the poor cousin, often overlooked and all too often neglected. Colleges, students and staff won't let Mike Russell spin his way out of the mess he's created."
The Scottish Government commitment to maintain student numbers so colleges have the equivalent of 116,000 full-time students has been met, with the equivalent of 119,448 full-time learners in 2011-12, the figures show.
Meanwhile more students are achieving their qualifications at college. In 2011-12 almost two-thirds of full-timers (64%) studying towards a recognised qualification successfully completed their course, up from three-fifths (60%) in 2009-10.
Education Secretary Mike Russell hailed the figures as "excellent news" for colleges. "Not only are our student numbers targets being exceeded but more young people than ever before are benefiting from full-time courses and more are successfully completing their studies. This is especially true for young people from more disadvantaged backgrounds," he said.