The violinist said: "I have wanted to do something like this for years as an extension of my music education work. I'm just delighted to have the support of Glasgow Unesco City of Music, Creative Scotland, the National Youth Orchestras of Scotland (NYOS) and the Royal Conservatoire of Scotland.
"I really hope the weekend will be insightful and enjoyable for the 40 young people and children participating but also for the public who come join in and watch our performances and sessions.
"It will also be great to be back in Scotland, as the weekend falls during my Silver Violin Tour. In the preceding months, I will have been to Scandinavia, Europe, USA and South East Asia, so it will be a relief to be spending such a long time back at home."
Creative Scotland's director of creative development Iain Munro said: "The Benedetti sessions will provide a brilliant opportunity for young musicians to learn from one of the most highly sought-after performers on the world stage.
"Nicola's passion and commitment to enhancing and developing young creative talent is to be applauded and helps ensure Scotland's creative future flourishes. We look forward to experiencing the outcome of the sessions at the public performance."